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Bierman Autism Centers Expansion Events in Indiana

Bierman Autism Centers Expansion Events in Indiana

INDIANAPOLIS, May 10, 2022 /PRNewswire/ — Bierman Autism Centers is holding two events this month as they continue to grow and offer ABA therapy services for children diagnosed with autism. This Indiana headquartered organization was founded 16 years ago and is a pillar of the community with four centers throughout the state.

The first event they are holding this month is an open house event for the community at their Avon center located at 5250 E US Hwy 36. This center opened this past July and the Bierman team is excited to show the community their new space! This is a great opportunity for families to tour the center, meet the team and learn more about the Bierman experience. The event will be on May 11th from 5:30pm to 7:30pm.

The second event is their first in-person hiring event for their Broad Ripple center! This is a great opportunity for anyone interested in healthcare or education who are looking to get into the field. There will be a food truck, music, and the opportunity to meet with the team and tour the center. This event will be on May 19th from 5pm to 7pm. The address for the event is 6060 N. College Ave, Indianapolis.

The Regional Director for Indiana, Jessica Fitch, says: “It’s very exciting to reopen our doors to the community after the pandemic. We are excited to show families and potential candidates how we deliver success as unique as our kids”.

The events are an opportunity to visit and see how Bierman delivers on its mission to create progress and possibilities for children with autism.

ABOUT BIERMAN www.biermanautism.com

Bierman Autism Centers is a place where kids as young as 18 months to 9 years of age engage in play to learn foundational skills they can build on such as self-advocacy and communication. For more about Bierman Autism Centers visit www.biermanautism.com or contact Alexis Ducharme at [email protected].

SOURCE Bierman Autism Centers

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Their Voice: Events past, present celebrate those with autism

Their Voice: Events past, present celebrate those with autism


Before we end the month of April, a month designated as Autism Awareness Month, I wanted to share some information about a research project taking place at BYU.

The study is focused on preschool-aged children diagnosed in the autism spectrum. They are asking for mothers of children between the ages of 2-5 years of age to participate in an autism research study. The mothers are required to be available for live virtual meetings on Tuesdays from 6:30-8:30 pm.

Depending on the participation category the study may include parent participation in up to 8 online teaching workshops, assessments and shared reading of provided books. Parents can earn a $25 gift card upon completion.

If you are interested in participating, go to the website https://autismbehaviorlab.byu.edu/current-research to see if you qualify. For any more information, contact Blake Hansen at 801-422-4691.

Speaking of autism, as we wind down from the events, I wanted to give a personal thank you to all of the members of the Autism Resources of Utah County Council (ARUCC) for the very successful 10th Annual Uplifting Celebration on April 16.

According to Laurie Bowen, associate director of the Melisa Nellesen Center for Autism at UVU, there were over 900 people in attendance with over 33 organizations providing food, games and other activities. The group of volunteers this year included many young adults who were on the spectrum.

As a participating sponsor, we provided a table for people to create greeting cards to send to the children in Ukraine. The cards were beautifully done and contained very heartfelt messages of hope, peace and love. It was touching to realize how many individuals in the autism community wanted to do something to send their well wishes. The 53 cards that were made are being sent over to Ukraine with the help of Orem City Police Chief Josh Adams, who recently returned from a humanitarian trip there that he organized with his good friend Jared Turner.

Thanks to all of the ARUCC and all of the organizations who worked so hard to make this day a success.



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Study provides insights into how early life events can affect brain wiring patterns

Study provides insights into how early life events can affect brain wiring patterns

A new study of brain development in mice shortly after birth may provide insights into how early life events can affect wiring patterns in the brain that manifest as disease later in life – specifically such disorders as schizophrenia, epilepsy and autism.

Researchers focused on two types of brain cells that have been linked to adult neurological disorders: neurons in a modulating system nestled deep in the brain and other neurons in the cortex, the brain’s outermost layer, that counteract excitation in other cells using inhibitory effects. The modulating cells send long-range cables to the cortex to remotely influence cortical cell activity.

The study is the first to show that these two types of cells communicate very early in brain development. A chemical released from the modulating cells initiates the branching, or arborization, of axons, the long, slender extensions of nerve cell bodies that transmit messages, on the cortical cells – and that arborization dictates how effective the cells in the cortex are at doing their job.

Though there is still a lot to learn about the impact of this cellular interaction in the postnatal brain, the researchers said the study opens the door to a better understanding of how neurological diseases in adults may relate to early-life events.

It’s known that abnormal early-life experiences can impact kids’ future sensation and behavior. This finding may help explain that kind of mechanism.”


Hiroki Taniguchi, associate professor of pathology, The Ohio State University College of Medicine and senior author of the study

“This study provides new insight into brain development and brain pathology. It’s possible that during development, depending on animals’ experiences, this modulating system activity can be changed and, accordingly, the cortical circuit wiring can be changed.”

Taniguchi completed the work with co-authors André Steinecke and McLean Bolton while he was an investigator at the Max Planck Florida Institute for Neuroscience.

The research is published today (March 9, 2022) in the journal Science Advances.

The study involved chandelier cells, a type of inhibitory neurons in the cortical section of the brain, and neurons of the cholinergic system – one of the systems that monitor the environment and the internal state, and send signals to the rest of the brain to trigger memory and appropriate behaviors.

“Both of these types of cells have been separately studied in the context of adult functions or modulations so far. The developmental role of cholinergic neurons in the brain wiring remains poorly understood,” Taniguchi said.

Chandelier cells are named for the spray of signal-transmitting synapses (called synaptic cartridges) at the branch terminals that resemble candles of a traditional chandelier, a pattern that gives them inhibitory control over hundreds of cells at a time.

“These cells have output control,” said Steinecke, first author of the study who is now working at Neuway Pharma in Germany. “Chandelier cells can put a brake on excitatory cells and tell them they’re not ready to fire. As inhibitory cells, chandelier cells are thought to regulate waves of firing – which is important, because the waves contain information that is transmitted over large distances of the brain.”

Previous post-mortem studies have shown that the synaptic terminals located at the end of chandelier cell axons appear to be reduced in the brains of patients with schizophrenia.

“This axonal ‘arbor’ being reduced suggests they don’t make as many connections to downstream targets, and the connections themselves are also altered and don’t work that well,” Steinecke said.

The team used two techniques to observe chandelier cells during early-life brain development in mice: genetically targeting and using a dye to label and detect cells that differentiate into chandelier cells, and transplanting genetically manipulated cells back into animals shortly after birth. “This enabled us to watch brain development as it happens and manipulate conditions to test what the mechanisms are,” Taniguchi said.

The researchers first observed how chandelier cell axons develop their branching structures, noting that small protrusions emerging from axons were the first signs that branches would sprout. And they identified the chemical needed to start that sprouting process – the neurotransmitter acetylcholine, which is released by cholinergic system cells.

The interaction between the distant cell types was confirmed through a series of experiments: Knocking out receptors that bind to acetylcholine and decreasing activity of cholinergic neurons lessened branch development, and making cholinergic neurons more likely to fire led to more widespread branching.

“The key is that we didn’t previously know how neuromodulatory systems regulate the cortical circuits – and both of them have been implicated in brain diseases,” Taniguchi said. “Now that we’ve found that cholinergic neurons could remotely impact cortical circuit development, especially cortical inhibitory signals, the question is what kind of environment or emotional state of change can impact cortical inhibitors’ development? We may want to see if we can find a link as a next step.”

This work was supported by funding from the Max Planck Society and the Brain Behavior and Research Foundation.

Source:

Journal reference:

Steinecke, A., et al. (2022) Neuromodulatory control of inhibitory network arborization in the developing postnatal neocortex. Science Advances. doi.org/10.1126/sciadv.abe7192.